Origin of the 1918 Spanish influenza virus: a comparative genomic analysis.
Identifieur interne : 000541 ( Main/Exploration ); précédent : 000540; suivant : 000542Origin of the 1918 Spanish influenza virus: a comparative genomic analysis.
Auteurs : Geoff Vana [États-Unis] ; Kristi M. WestoverSource :
- Molecular phylogenetics and evolution [ 1055-7903 ] ; 2008.
Descripteurs français
- KwdFr :
- MESH :
- génétique : ADN concaténé, Génome viral, Virus de la grippe A.
- Espagne, Humains, Phylogenèse.
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : DNA, Concatenated.
- geographic : Spain.
- genetics : Genome, Viral, Influenza A virus.
- Humans, Phylogeny.
Abstract
To test the avian-origin hypothesis of the 1918 Spanish influenza virus we surveyed influenza sequences from a broad taxonomic distribution and collected 65 full-length genomes representing avian, human and "classic" swine H1N1 lineages in addition to numerous other swine (H1N2, H3N1, and H3N2), human (H2N2, H3N2, and H5N1), and avian (H1N1, H4N6, H5N1, H6N1, H6N6, H6N8, H7N3, H8N4, H9N2, and H13N2) subtypes. Amino acids from all eight segments were concatenated, aligned, and used for phylogenetic analyses. In addition, the genes of the polymerase complex (PB1, PB2, and PA) were analyzed individually. All of our results showed the Brevig-Mission/1918 strain in a position basal to the rest of the clade containing human H1N1s and were consistent with a reassortment hypothesis for the origin of the 1918 virus. Our genome phylogeny further indicates a sister relationship with the "classic" swine H1N1 lineage. The individual PB1, PB2, and PA phylogenies were consistent with reassortment/recombination hypotheses for these genes. These results demonstrate the importance of using a complete-genome approach for addressing the avian-origin hypothesis and predicting the emergence of new pandemic influenza strains.
DOI: 10.1016/j.ympev.2008.02.003
PubMed: 18353690
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Origin of the 1918 Spanish influenza virus: a comparative genomic analysis.</title><author><name sortKey="Vana, Geoff" sort="Vana, Geoff" uniqKey="Vana G" first="Geoff" last="Vana">Geoff Vana</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biology, Winthrop University, Rock Hill, SC 29733, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, Winthrop University, Rock Hill, SC 29733</wicri:regionArea><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Westover, Kristi M" sort="Westover, Kristi M" uniqKey="Westover K" first="Kristi M" last="Westover">Kristi M. Westover</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2008">2008</date><idno type="RBID">pubmed:18353690</idno><idno type="pmid">18353690</idno><idno type="doi">10.1016/j.ympev.2008.02.003</idno><idno type="wicri:Area/Main/Corpus">00543</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">00543</idno><idno type="wicri:Area/Main/Curation">000543</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000543</idno><idno type="wicri:Area/Main/Exploration">000543</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Origin of the 1918 Spanish influenza virus: a comparative genomic analysis.</title><author><name sortKey="Vana, Geoff" sort="Vana, Geoff" uniqKey="Vana G" first="Geoff" last="Vana">Geoff Vana</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biology, Winthrop University, Rock Hill, SC 29733, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, Winthrop University, Rock Hill, SC 29733</wicri:regionArea><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Westover, Kristi M" sort="Westover, Kristi M" uniqKey="Westover K" first="Kristi M" last="Westover">Kristi M. Westover</name></author></analytic><series><title level="j">Molecular phylogenetics and evolution</title><idno type="ISSN">1055-7903</idno><imprint><date when="2008" type="published">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>DNA, Concatenated (genetics)</term><term>Genome, Viral (genetics)</term><term>Humans (MeSH)</term><term>Influenza A virus (genetics)</term><term>Phylogeny (MeSH)</term><term>Spain (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ADN concaténé (génétique)</term><term>Espagne (MeSH)</term><term>Génome viral (génétique)</term><term>Humains (MeSH)</term><term>Phylogenèse (MeSH)</term><term>Virus de la grippe A (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>DNA, Concatenated</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Genome, Viral</term><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ADN concaténé</term><term>Génome viral</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Phylogeny</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Espagne</term><term>Humains</term><term>Phylogenèse</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To test the avian-origin hypothesis of the 1918 Spanish influenza virus we surveyed influenza sequences from a broad taxonomic distribution and collected 65 full-length genomes representing avian, human and "classic" swine H1N1 lineages in addition to numerous other swine (H1N2, H3N1, and H3N2), human (H2N2, H3N2, and H5N1), and avian (H1N1, H4N6, H5N1, H6N1, H6N6, H6N8, H7N3, H8N4, H9N2, and H13N2) subtypes. Amino acids from all eight segments were concatenated, aligned, and used for phylogenetic analyses. In addition, the genes of the polymerase complex (PB1, PB2, and PA) were analyzed individually. All of our results showed the Brevig-Mission/1918 strain in a position basal to the rest of the clade containing human H1N1s and were consistent with a reassortment hypothesis for the origin of the 1918 virus. Our genome phylogeny further indicates a sister relationship with the "classic" swine H1N1 lineage. The individual PB1, PB2, and PA phylogenies were consistent with reassortment/recombination hypotheses for these genes. These results demonstrate the importance of using a complete-genome approach for addressing the avian-origin hypothesis and predicting the emergence of new pandemic influenza strains.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">18353690</PMID><DateCompleted><Year>2008</Year><Month>08</Month><Day>08</Day></DateCompleted><DateRevised><Year>2008</Year><Month>05</Month><Day>28</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">1055-7903</ISSN><JournalIssue CitedMedium="Print"><Volume>47</Volume><Issue>3</Issue><PubDate><Year>2008</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Molecular phylogenetics and evolution</Title><ISOAbbreviation>Mol. Phylogenet. Evol.</ISOAbbreviation></Journal><ArticleTitle>Origin of the 1918 Spanish influenza virus: a comparative genomic analysis.</ArticleTitle><Pagination><MedlinePgn>1100-10</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ympev.2008.02.003</ELocationID><Abstract><AbstractText>To test the avian-origin hypothesis of the 1918 Spanish influenza virus we surveyed influenza sequences from a broad taxonomic distribution and collected 65 full-length genomes representing avian, human and "classic" swine H1N1 lineages in addition to numerous other swine (H1N2, H3N1, and H3N2), human (H2N2, H3N2, and H5N1), and avian (H1N1, H4N6, H5N1, H6N1, H6N6, H6N8, H7N3, H8N4, H9N2, and H13N2) subtypes. Amino acids from all eight segments were concatenated, aligned, and used for phylogenetic analyses. In addition, the genes of the polymerase complex (PB1, PB2, and PA) were analyzed individually. All of our results showed the Brevig-Mission/1918 strain in a position basal to the rest of the clade containing human H1N1s and were consistent with a reassortment hypothesis for the origin of the 1918 virus. Our genome phylogeny further indicates a sister relationship with the "classic" swine H1N1 lineage. The individual PB1, PB2, and PA phylogenies were consistent with reassortment/recombination hypotheses for these genes. These results demonstrate the importance of using a complete-genome approach for addressing the avian-origin hypothesis and predicting the emergence of new pandemic influenza strains.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vana</LastName><ForeName>Geoff</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Biology, Winthrop University, Rock Hill, SC 29733, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Westover</LastName><ForeName>Kristi M</ForeName><Initials>KM</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>P20 RR-016461</GrantID><Acronym>RR</Acronym><Agency>NCRR NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2008</Year><Month>02</Month><Day>14</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mol Phylogenet Evol</MedlineTA><NlmUniqueID>9304400</NlmUniqueID><ISSNLinking>1055-7903</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D044708">DNA, Concatenated</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D044708" MajorTopicYN="N">DNA, Concatenated</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016679" MajorTopicYN="N">Genome, Viral</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2007</Year><Month>09</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2008</Year><Month>02</Month><Day>05</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2008</Year><Month>02</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2008</Year><Month>3</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2008</Year><Month>8</Month><Day>9</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2008</Year><Month>3</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">18353690</ArticleId><ArticleId IdType="pii">S1055-7903(08)00064-X</ArticleId><ArticleId IdType="doi">10.1016/j.ympev.2008.02.003</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Caroline du Sud</li></region></list><tree><noCountry><name sortKey="Westover, Kristi M" sort="Westover, Kristi M" uniqKey="Westover K" first="Kristi M" last="Westover">Kristi M. Westover</name></noCountry><country name="États-Unis"><region name="Caroline du Sud"><name sortKey="Vana, Geoff" sort="Vana, Geoff" uniqKey="Vana G" first="Geoff" last="Vana">Geoff Vana</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippeEspagneV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000541 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000541 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= GrippeEspagneV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:18353690
|texte= Origin of the 1918 Spanish influenza virus: a comparative genomic analysis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:18353690" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a GrippeEspagneV1
| This area was generated with Dilib version V0.6.37. |  |